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Trough medical definition

WebNov 9, 2024 · Therapeutic drug monitoring is the measurement of specific drugs and/or their breakdown products (metabolites) at timed intervals to maintain a relatively constant concentration of the medication in the blood. Some of the monitored drugs tend to have a narrow “therapeutic index,” which is a ratio between the toxic and therapeutic (effective ... WebPeak-to-trough ratio ( PTR ), also known as peak-to-trough variation or peak-to-trough fluctuation, is a parameter in pharmacokinetics which is defined as the ratio of C max (peak) concentration and C min (trough) concentration over a dosing interval for a given drug.

What does trough mean? - Definitions.net

Webtrough n. figurative (economy: lowest point) depresión nf. Economists believe we are past the trough of the recession. Los economistas creen que ya pasamos la depresión de la recesión. trough n. (weather: low pressure) (Meteorología) vaguada nf. WebPeak and trough levels indicate drug levels in an individual’s body. A peak is the highest level of a medication in the blood, while a trough level indicates the lowest concentration. … hbd231cr61 bosch https://johntmurraylaw.com

Therapeutic Drugs - Optimal Time to Draw Samples - NHRMC

WebTrough concentrations are recommended for therapeutic monitoring of vancomycin, preferably acquired at steady-state (just before fourth dose). To avoid development of resistance, vancomycin trough levels should remain above 10.0 mcg/mL. Complicated infections require higher target levels, typically 15.0 to 20.0 mcg/mL. WebPeak-to-trough ratio (PTR), also known as peak-to-trough variation or peak-to-trough fluctuation, is a parameter in pharmacokinetics which is defined as the ratio of C max … WebHow to pronounce trough. How to say trough. Listen to the audio pronunciation in the Cambridge English Dictionary. Learn more. hbd230cr61

Trough Definition & Meaning - Merriam-Webster

Category:peak and trough - Medical Dictionary

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Trough medical definition

Peaks and Troughs - LabCE.com, Laboratory Continuing Education

WebMar 24, 2024 · Peak And Trough Medical Definition. Accuracy, as formally defined, and the elements that contribute to it can be. the maximum or peak concentration (cmax) of a drug observed after its. As nouns the difference between peak and trough is that peak is a point; the sharp end or top of anything that terminates in a point; as, the peak, or front, of ... Webtrough (trôf, trŏf) n. 1. a. A long, narrow, generally shallow receptacle for holding water or feed for animals. b. Any of various similar containers for domestic or industrial use, such as kneading or washing. 2. A gutter under the edge of a roof for carrying off rainwater. 3. A long, narrow depression, as between waves or ridges. 4.

Trough medical definition

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WebSynonyms of trough 1 a : a long shallow often V-shaped receptacle for the drinking water or feed of domestic animals b : any of various domestic or industrial containers 2 a : a … Webtrough / ( trɒf) / noun a narrow open container, esp one in which food or water for animals is put a narrow channel, gutter, or gulley a narrow depression either in the land surface, …

WebTrough concentrations are recommended for therapeutic monitoring of vancomycin, preferably acquired at steady-state (just before fourth dose). To avoid development of … WebThe trough is the lowest level of the drug while in the therapeutic range. Obtain Before Next Dose Obtaining Blood Before Next Dose A trough level should be drawn before the next dose is due, and helps determine if the next dose needs to be adjusted, depending on the results.

WebTrough. In a recession, the point of the most negative GDP growth that immediately precedes the beginning of recovery. In other words, it is the lowest point in a business cycle. The term comes from charting, in which the x-axis represents time and the y-axis represents GDP growth. In this situation, the low point of a business cycle looks like ... WebTrough: Collect just prior to next dose Peak: Draw 1 ½ hours after IV infusion has completed. References: Interpretation in Therapeutic Drug Monitoring, Daniel Baer and …

WebFeb 6, 2024 · This definition is probably the most suitable because it is short and generic. It also allows for an idiosyncratic lack of a reaction, i.e an individual who is uniquely insensitive to a substance. It opens the possibility that the reaction is an extension of the therapeutic effect of the drug (unlike Uetrecht & Nasibitt) and it does not ...

WebDec 11, 2008 · Trough is the lowest drug level that is needed to reach therapeutic range. If trough is > than normal, the patient is at risk for adverse effects. Therefore, the doctor … hbd431as61Webtrough. ( trawf) 1. Long, narrow, shallow channel or depression. 2. Lowest point in variable measurement. Medical Dictionary for the Dental Professions © Farlex 2012. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, or visit the … trough (trôf, trŏf) n. 1. a. A long, narrow, generally shallow receptacle for holding … Looking for online definition of trough or what trough stands for? trough is listed … In a recession, the point of the most negative GDP growth that immediately … trough 1. a narrow depression either in the land surface, ocean bed, or between two … Trousseau's sign: [ troo-sōz´ ] 1. spontaneous peripheral venous … trough level: ( trawf lev'ĕl ) The lowest concentration reached by a drug before … arm trough: A concave positioning device attached to a wheelchair armrest that … Definition of trough in the Idioms Dictionary. trough phrase. What does trough … trough sign: an anteromedial glenoid defect resultant from posterior shoulder … abnormality: [ ab″nor-mal´ĭ-te ] 1. the state of being unlike the usual condition. 2. a … hbd431fh63WebThe lowest level of the drug in the patient's body is called the trough level. The peak for a drug is when the level of the drug in the patient's body is the highest. To assess drug … gold and economic growth in nigeriaWebDefinition of trough level in the Definitions.net dictionary. Meaning of trough level. What does trough level mean? Information and translations of trough level in the most comprehensive dictionary definitions resource on the web. Login . The STANDS4 Network. ABBREVIATIONS; ANAGRAMS; BIOGRAPHIES; CALCULATORS; CONVERSIONS; … hbd431fh60hbd415rs61WebJan 21, 2024 · After the target AUC or trough level is achieved at steady state, trough levels should be checked every 2 to 5 days until completion of therapy or discharge. Check peak/trough after any dose initiation/change. i. Levels should be checked sooner when clinically warranted (i.e.: change in clinical status or hbd431as60Webtrough answers are found in the Taber's Medical Dictionary powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web. gold and economy